OcellO is always looking for motivated and talented people to join the team

OcellO is a young company based on the Leiden BioScience park in The Netherlands. OcellO offers cutting-edge technology in the field of high content analysis and drug discovery to partnered projects and customers. We are always looking for colleagues to join the team — colleagues who will thrive in a dynamic environment and will make an important contribution to OcellO’s continued growth and success. If you are highly motivated, get on well with people, are scientifically talented and organisationally competent and are looking for a stimulating job then send your CV and a letter to

jobs@ocello.nl

 

At the moment we have 1 vacancy:

  • – 6-9 month research internship project

See full description below.

 

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6-9 month research internship project

 

Testing novel drugs and drug targets in 3D cultured isogenic tumour models

 

Start date: from August 2017.
Location: Biopartner2, Leiden, The Netherlands

 

OcellO is a fast-growing innovative biotech company offering unique 3D cell culture-based screening services that accelerate pre-clinical drug discovery in oncology and inherited diseases, such as cystic fibrosis and polycystic kidney disease.  OcellO best-in-class technology meets a growing need for improved in vitro testing to predict drug responses in pre-clinical models and patients and reduce drug development costs. Founded in 2011, OcellO provides services for many of the leading global pharmaceutical companies. OcellO has an active R&D program to maintain its leading position as a provider of advanced tissue based assays.

 

Conventional in vitro testing models involve the culture of cell lines on plastic tissue culture, which obviously is nothing like the situation in human tumours. At OcellO, we develop 3D cell culture models for high content screening of compounds using a unique 3D screening platform.  In this project, isogenic pairs of human tumours which are wild type or mutant for key oncogenes will be cultured as mini-tumours in 3D. These will be tested with novel and established drugs that target the oncogenic pathway.  Outcomes of the project will be novel assays for targeting specific oncogenic pathways.

 

The research will be performed at the labs of OcellO, which has developed a platform for screening, which includes automated 3D culture, drug exposure, microscopy based imaging and data analysis.  Office space and computer facilities etc. will also be provided at OcellO.

 

Techniques and activities will include:

  • Internet-based study of the academic literature
  • 2D and 3D cell cultures
  • Robotics and automated liquid handling
  • Immunofluorescence labeling and microscopy
  • Automated microscopy imaging
  • Bioinformatics analysis of data
  • Diligent maintenance of lab book

 

If you are interested in this position, please send a copy of your CV and a letter of motivation to: jobs@ocello.nl.

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OcellO pursues a non-discriminatory employment policy and values equal opportunities, as well as diversity.